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Chapter 2. Basic Principles of Molecular Biology and Genomics

Jiang-Zhou Yu, M.D., Ph.D.; Mark M. Rasenick, Ph.D.
DOI: 10.1176/appi.books.9781585623860.416279

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In June 2000, it was announced that both a corporate effort and a government consortium had succeeded in sequencing all of the human genome. This was followed by the publication of that sequence in February 2001 (Lander et al. 2001; Venter et al. 2001). For anyone involved in biology or medicine, these events represented a revolution in the technical and conceptual approach to both research and therapy.

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Sample questions:
1.
As a result of the sequencing of all of the human genome, the number of human genes was estimated to be
2.
Genes undergo a process in which an RNA molecule complementary to one of the gene’s DNA strands is synthesized using nucleotide triphosphates. What is this process called?
3.
A rapid procedure for in vitro enzymatic amplification of specific segments of DNA is called
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