History and Discovery | Structure–Activity Relations | Pharmacokinetics and Disposition | Mechanism of Action | Therapeutic Uses | Side Effects and Toxicology | Drug–Drug Interactions | Clinical Issues | Medicolegal Issues | Conclusion | References
In spite of adverse publicity and a problematic public image,
the most widely prescribed psychiatric medication in the United
States over the past several years is not an antidepressant, an
atypical antipsychotic, or a mood stabilizer but the benzodiazepine
alprazolam, with 31 million prescriptions issued in 2001 (see Stahl 2002).